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Table 1 Clinical and biochemical characteristics of the study subjects

From: Normal-weight obesity is associated with increased risk of subclinical atherosclerosis

 

Entire population n = 2078

NWL n = 1795

NWO n = 283

P-value

Age (yr)

53.4 ± 9.2

52.8 ± 9.2

57.6 ± 8.2

<0.001

Male (n, %)

1141 (54.9)

1026 (57.2)

115 (40.6)

<0.001

Smoking status

   

0.003

 Current smoker (n, %)

369 (17.8)

332 (18.5)

37 (13.1)

 

 Ex-smoker (n, %)

557 (29.1)

494 (27.5)

63 (22.3)

 

 Non-smoker (n, %)

1152 (55.4)

969 (54.0)

183 (64.7)

 

Systolic BP (mmHg)

123.4 ± 15.6

122.5 ± 15.5

128.6 ± 15.7

<0.001

Diastolic BP (mmHg)

77.0 ± 10.1

76.6 ± 10.1

79.6 ± 9.3

<0.001

BMI

22.37 ± 1.7

22.53 ± 4.3

23.9 ± 0.8

<0.001

Body fat percentage (%)

24.4 ± 4.8

23.5 ± 4.3

30.1 ± 3.4

<0.001

Visceral fat (kg)

1.9 ± 0.5

1.75 ± 0.5

2.50 ± 0.4

<0.001

Subcutaneous fat (kg)

12.9 ± 2.5

12.5 ± 2.2

16.0 ± 1.6

<0.001

Fasting glucose (mg/dL)

96.1 ± 17.3

95.7 ± 17.5

99.1 ± 15.9

0.004

Total cholesterol (mg/dL)

193.5 ± 34.8

192.5 ± 34.6

199.6 ± 35.5

0.017

Triglyceride (mg/dL)

107.8 ± 64.9

106.4 ± 65.1

116.6 ± 63.3

<0.001

HDL-cholesterol (mg/dL)

50.8 ± 12.7

51.0 ± 12.8

49.6 ± 11.3

0.002

LDL-cholesterol (mg/dL)

118.0 ± 30.9

117.1 ± 30.6

123.9 ± 32.2

0.002

ALT (IU/L)

22.5 ± 17.35

21.9 ± 17.5

26.4 ± 15.87

<0.001

CRP (mg/L)

1.2 ± 2.0

1.2 ± 2.0

1.6 ± 2.3

0.003

Hypertension (n, %)

697 (33.5)

555 (30.9)

142 (50.2)

<0.001

Diabetes mellitus (n, %)

221 (10.6)

184 (10.3)

37 (13.1)

0.656

BP medication (n, %)

409 (19.7)

319 (17.8)

90 (31.8)

<0.001

Diabetes medication (n, %)

145 (7.0)

118 (6.6)

27 (9.5)

0.677

Lipid lowering agent (n, %)

214 (10.3)

169 (9.4)

45 (15.9)

0.181

Antiplatelet agent (n, %)

223 (10.7)

186 (10.4)

37 (13.1)

0.971

Fatty liver (n, %)

671 (32.3)

531 (29.6)

140 (49.5)

<0.001

Alcohol intake (cup/month)

32.4 ± 11.8

34.0 ± 64.2

22.03 ± 48.4

0.867

Excessive salt intake (n, %)

459 (25.1)

395 (25.0)

64 (25.6)

0.283

Physical activity (n, %)

1432 (73.7)

1245 (74.5)

187 (69.0)

0.049

  1. NWO normal weight obesity, NWL normal weight lean, BP blood pressure, BMI body mass index, HDL-cholesterol high-density lipoprotein cholesterol, LDL-cholesterol low-density lipoprotein cholesterol, ALT alanine transaminase, CRP C-reactive protein. The difference of age, sex and smoking status between the NWL and the NWO subjects was analyzed with either Student’s t-test or χ2-test as appropriate. The difference of all other variables was analyzed with analysis of covariance (ANCOVA) using age, sex, and smoking status as covariates. Continuous variables are presented as mean ± standard deviation. Dichotomous variables are presented as the number of subjects with the percentage of subjects in the parenthesis