Skip to main content
Fig. 8 | Cardiovascular Diabetology

Fig. 8

From: DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice

Fig. 8

Effect of 7 days of linagliptin administration on IgG extravasation and cerebral claudin-5 in the brain of db/db mice subjected to transient BCCAO. a indicates representative image of IgG immunostained cerebral section of each group and (b) indicates relative density of IgG staining. Bar = 2 mm. (c) indicates relative density of cerebral claudin-5 estimated by western blot. Upper panels in (c) indicate representative western blot band. In individual mouse, claudin-5 wes corrected for GAPDH. Abbreviations used are the same as in Fig. 3. Each value represents mean ± SEM (n = 7 in Sham, n = 6 in BCCAO + Veh, n = 7 in BCCAO + Lin.)

Back to article page