Fig. 2

Representative subtracted angiograms of the hindlimb vasculature in control (Ctrl), diabetic (Stz), and treadmill running diabetic (Exe) mice during baseline (upper panels) and following administration of acetylcholine (1.0 μg/kg/min, lower). The original image was subtracted by background image captured before contrast agent injection to enhance the edge of vessels. Scale bar = 1 mm