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Table 4 The multiple regression analysis with clot permeability and lysis time as the dependent variables

From: Low fasting glucose is associated with enhanced thrombin generation and unfavorable fibrin clot properties in type 2 diabetic patients with high cardiovascular risk

Dependent variable Independent variables P -value Coefficient 95.0% CI
Clot permeability PF4 <0.001 −0.46 −0.57 −0.33
R = 0.62, R2 = 0.38, Fibrinogen <0.001 −0.27 −0.41 −0.12
F(6, 156) = 13.8, p < 0.0001 HbA1c 0.002 −0.19 −0.33 −0.04
DM duration 0.005 −0.22 −0.36 −0.07
Glucose 0.002 0.61 0.50 0.70
Glucose squared 0.008 −0.56 −0.66 −0.44
Lysis time PF4 <0.001 0.41 0.27 0.53
R = 0.58, R2 = 0.34, Fibrinogen <0.001 0.22 0.07 0.36
F(6, 156) = 11.4, P < 0.0001 DM duration 0.002 0.25 0.10 0.39
HbA1c 0.002 0.20 0.05 0.34
Glucose 0.008 −0.47 −0.58 −0.32
Glucose squared 0.045 0.30 0.15 0.43
Peak thrombin generation Glucose <0.001 −0.97 −0.98 −0.96
R = 0.51, R2 = 0.26, Glucose squared 0.014 0.83 0.77 0.87
F(6, 155) = 8.8, P < 0.0001 Fibrinogen 0.002 0.22 0.07 0.36
DM duration 0.005 0.21 0.06 0.35
HbA1c 0.015 0.21 0.06 0.36
Age 0.03 −0.15 −0.30 0
  1. Abbreviations: as in Tables 1 and 2.