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Table 2 Characteristics of subjects categorized by albumin-adjusted serum calcium quartiles

From: Cross-sectional analysis of serum calcium levels for associations with left ventricular hypertrophy in normocalcemia individuals with type 2 diabetes

Characteristics

Albumin-adjusted calcium concentration (mg/dL)

P value

8.42-8.69

8.70-8.93

8.94-9.22

9.23-10.42

n

213

237

181

202

Age (year)

 

67.9 ± 11.4

66.6 ± 13.3

68.3 ± 12.6

68.4 ± 12.9

0.188

Male, n (%)

 

142 (66.7)

143 (60.3)

99 (54.7)

102 (50.5)

0.006

Hypertension, n (%)

 

105 (49.3)

120 (50.6)

89 (49.2)

115 (56.9)

0.353

ACEI/ARB use, n (%)

 

101 (47.4)

98 (41.4)

76 (42.0)

103 (51.0)

0.150

Smoking, n (%)

 

57 (26.8)

54 (22.8)

37 (20.4)

42 (20.8)

0.402

Duration of diabetes (year)

 

10.1 ± 8.0

10.4 ± 9.1

10.7 ± 8.1

10.4 ± 8.7

0.041

SBP (mmHg)

 

137.1 ± 19.2

137.8 ± 19.6

135.4 ± 21.6

137.2 ± 18.3

0.672

DBP (mmHg)

 

79.2 ± 10.0

79.6 ± 11.2

79.5 ± 12.2

78.8 ± 10.8

0.894

BMI (kg/m2)

 

24.5 ± 3.4

24.5 ± 4.1

24.3 ± 4.0

24.0 ± 3.8

0.105

Obesity, n (%)

 

25 (11.7)

37 (15.6)

31 (17.1)

31 (15.3)

0.472

Laboratory

      
 

FPG (mmol/L)

7.04 ± 1.97

7.57 ± 2.82

7.88 ± 3.04

8.92 ± 4.16

< 0.001

 

lg HOMA-IR

0.53 ± 0.30

0.57 ± 0.32

0.61 ± 0.33

0.63 ± 0.36

0.011

 

HbA1c (%)

8.12 ± 1.96

7.94 ± 1.74

8.17 ± 1.95

8.34 ± 2.06

0.181

 

Albumin (g/L)

39.72 ± 4.42

38.90 ± 5.44

38.91 ± 4.16

36.85 ± 5.14

0.002

 

Uric acid (μmol/L)

320.68 ± 95.21

336.17 ± 97.88

336.90 ± 98.26

359.72 ± 113.81

0.913

 

Creatinine (μmol/L)

78.36 ± 20.31

83.13 ± 25.94

82.61 ± 24.86

85.24 ± 26.32

0.531

 

lg Alb/Cr (mg/g)

1.60 ± 0.71

1.65 ± 0.72

1.79 ± 0.68

1.83 ± 0.66

< 0.001

 

Micro-albuminuria, n (%)

107 (50.2)

126 (53.2)

113 (62.4)

130 (64.4)

0.007

 

TG (mmol/L)

1.79 ± 1.10

1.85 ± 1.17

1.73 ± 1.05

1.94 ± 1.39

0.329

 

TC (mmol/L)

4.59 ± 1.12

4.89 ± 1.07

4.77 ± 1.26

4.98 ± 1.19

0.003

 

HDL-C (mmol/L)

1.08 ± 0.31

1.12 ± 0.28

1.19 ± 0.56

1.06 ± 0.27

0.301

 

LDL-C (mmol/L)

2.63 ± 0.82

2.77 ± 0.79

2.62 ± 0.92

2.88 ± 0.85

0.004

 

Dyslipidemia, n (%)

114 (53.5)

123 (51.9)

87 (48.1)

124 (61.4)

0.060

 

albumin-adjusted-Calcium (mg/dL)

8.57 ± 0.08

8.84 ± 0.07

9.10 ± 0.08

9.52 ± 0.26

< 0.001

 

Phosphate (mg/dL)

3.48 ± 0.43

3.54 ± 0.44

3.61 ± 0.47

3.59 ± 0.49

0.021

LV dimension

 

LVIDD (mm)

47.56 ± 4.19

47.03 ± 4.82

47.22 ± 4.57

47.99 ± 4.42

0.142

 

LVIDS (mm)

29.89 ± 4.20

30.09 ± 3.62

30.49 ± 4.32

30.89 ± 4.46

0.066

 

IVSD (mm)

10.27 ± 1.45

10.84 ± 1.52

10.66 ± 1.59

11.13 ± 1.73

< 0.001

 

PWTD (mm)

9.48 ± 1.24

9.91 ± 1.34

9.93 ± 1.22

10.09 ± 1.45

< 0.001

 

RWT

0.40 ± 0.06

0.43 ± 0.08

0.42 ± 0.06

0.42 ± 0.07

< 0.001

 

LVMI (g/m2)

94.20 ± 19.02

101.51 ± 21.62

101.77 ± 22.65

111.21 ± 27.93

< 0.001

 

LVEF (%)

65.77 ± 7.45

64.68 ± 6.97

63.69 ± 8.26

64.87 ± 7.53

0.056

LV geometry

      
 

Normal (%)

54.0

40.9

35.4

31.2

< 0.001

 

Concentric remodeling (%)

23.0

21.5

27.6

15.3

 

Eccentric hypertrophy (%)

12.2

18.1

15.5

21.3

 

Concentric hypertrophy (%)

10.8

19.4

21.5

32.2

LVH, (%)

 

23.0

37.6

37.0

53.5

< 0.001