Table 2 Genotype distribution and allele frequencies of the rs8192673 of the PGC - 1α gene and rs1801282 of the PPAR - γ gene in subjects with T2DM and in control subjects
Polymorphism | T2DM n = 881 | Controls n = 348 | p |
|---|---|---|---|
rs8192673 | |||
TT | 467 (53.0) | 161 (46.3) | |
TC | 334 (37.9) | 147 (42.2) | 0.08 |
CC | 80 (9.1) | 40 (11.5) | |
Allele frequencies | |||
T | 1268 (71.9) | 469 (67.4) | 0.02 |
C | 494 (28.1) | 227 (32.6) | |
rs1801282 | |||
CC | 631 (71.6) | 250 (71.8) | 0.50 |
CG | 228 (25.9) | 85 (24.5) | |
GG | 22 (2.5) | 13 (3.7) | |
Allele frequencies | |||
C | 1490 (84.6) | 585 (84.1) | 0.06 |
G | 272 (15.4) | 111 (15.9) |