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Table 1 Characteristics of subjects with type 2 diabetes (cases) and in subjects without diabetes (controls)

From: Polymorphisms of the Peroxisome Proliferator-Activated Receptor-γ (rs1801282) and its coactivator-1 (rs8192673) are associated with obesity indexes in subjects with type 2 diabetes mellitus

Characteristics

Cases

Controls

P

Number

881

348

-

Age (years)

63.2 ± 10.3

61.3 ± 12.9

0.1

Male sex (%)

458 (52.0)

173 (49.7)

0.3

Duration of diabetes (years)

14.8 ± 8.9

-

-

Incidence of arterial hypertension (%)

458 (52.0)

103 (29.6)

<0.001

Systolic blood pressure (mm Hg)

148.9 ± 28.5

146.7 ± 22.7

0.06

Diastolic blood pressure (mm Hg)

84.9 ± 12.2

83.5 ± 11.8

0.3

BMI (kg/m2)1

30.4 ± 4.2

28.5 ± 3.5

<0.001

Obesity2

436 (49.5)

87 (25.0)

<0.001

Smokers (%)

61 (6.9)

45 (12.9)

<0.001

Glucose (mmol/l)

8.32 ± 2.52

5.18 ± 0.87

<0.001

Hba1c3

8.07 ± 1.54

-

-

hsCRP (mg/l)4*

2.1 (1.0-4.1)

1.1 (0.6-2.7)

<0.001

Fibrinogen (g/l)

4.10 ± 1.15

3.76 ± 0.83

<0.001

Hypolipemic drugs

698 (79.2)

66 (19.0)

<0.001

Total cholesterol (mmol/l)

5.5 ± 1.4

5.9 ± 1.6

<0.001

HDL cholesterol (mmol/l)

1.1 ± 0.3

1.3 ± 0.4

<0.001

LDL cholesterol (mmol/l)

2.6 ± 0.9

3.0 ± 1.1

<0.001

Triglycerides (mmol/l)*

1.9 (1.2-2.7)

1.3 (0.9-1.9)

<0.001

  1. Continuous variables were expressed as means ± standard deviations when normally distributed and as median (interquartile range) when asymmetrically distributed.
  2. 1BMI – body mass index, 2obesity is defined as BMI ≥ 30 kg/m2, 3Hba1c – glycated hemoglobin A1c, 4hsCRP – high sensitive C reactive protein, *Continuous variables with asymmetric distribution.