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Table 1 Characteristics of subjects with type 2 diabetes (cases) and in subjects without diabetes (controls)

From: Polymorphisms of the Peroxisome Proliferator-Activated Receptor-γ (rs1801282) and its coactivator-1 (rs8192673) are associated with obesity indexes in subjects with type 2 diabetes mellitus

Characteristics Cases Controls P
Number 881 348 -
Age (years) 63.2 ± 10.3 61.3 ± 12.9 0.1
Male sex (%) 458 (52.0) 173 (49.7) 0.3
Duration of diabetes (years) 14.8 ± 8.9 - -
Incidence of arterial hypertension (%) 458 (52.0) 103 (29.6) <0.001
Systolic blood pressure (mm Hg) 148.9 ± 28.5 146.7 ± 22.7 0.06
Diastolic blood pressure (mm Hg) 84.9 ± 12.2 83.5 ± 11.8 0.3
BMI (kg/m2)1 30.4 ± 4.2 28.5 ± 3.5 <0.001
Obesity2 436 (49.5) 87 (25.0) <0.001
Smokers (%) 61 (6.9) 45 (12.9) <0.001
Glucose (mmol/l) 8.32 ± 2.52 5.18 ± 0.87 <0.001
Hba1c3 8.07 ± 1.54 - -
hsCRP (mg/l)4* 2.1 (1.0-4.1) 1.1 (0.6-2.7) <0.001
Fibrinogen (g/l) 4.10 ± 1.15 3.76 ± 0.83 <0.001
Hypolipemic drugs 698 (79.2) 66 (19.0) <0.001
Total cholesterol (mmol/l) 5.5 ± 1.4 5.9 ± 1.6 <0.001
HDL cholesterol (mmol/l) 1.1 ± 0.3 1.3 ± 0.4 <0.001
LDL cholesterol (mmol/l) 2.6 ± 0.9 3.0 ± 1.1 <0.001
Triglycerides (mmol/l)* 1.9 (1.2-2.7) 1.3 (0.9-1.9) <0.001
  1. Continuous variables were expressed as means ± standard deviations when normally distributed and as median (interquartile range) when asymmetrically distributed.
  2. 1BMI – body mass index, 2obesity is defined as BMI ≥ 30 kg/m2, 3Hba1c – glycated hemoglobin A1c, 4hsCRP – high sensitive C reactive protein, *Continuous variables with asymmetric distribution.