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Table 2 Effects of Liraglutide (all three doses) on blood pressure and heart rate

From: Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats

 

BP (mmHg)

HR (bpm)

Baseline→treatment

Baseline→treatment

Saline alone

121.8 ± 5.0 116.0 ± 4.7

378.6 ± 9.5 360.1 ± 6.3

Lira 3 nmol/kg/h

125.5 ± 1.5124.9 ± 1.8

393.3 ± 7.8397.9 ± 12.2

Lira 9 nmol/kg/h

125.5 ± 1.5 127.3 ± 2.4

393.3 ± 7.8415.0 ± 12.6*

Lira 27 nmol/kg/h

125.5 ± 1.5 129.4 ± 1.8

393.3 ± 7.8425.9 ± 14.3*

  1. Lira, Liraglutide. *P < 0.05 post- vs. pre-treatment (baseline). In the saline alone group, BP and HR were not changed through the study; data shown in the table are the 1st and last study period. Baseline refers to the 20 minutes period prior to administration of saline or Liraglutide.