Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics

Table 5 Average axial ratios of the groups and significant differences between the groups

	Healthy individuals (no products added) (N = 25)	Untreated Diabetes (DIAB) (N = 69)	Diabetes with Deferasirox (DFX) (N = 69)	Diabetes with Deferoxamine (DFO) (N = 69)
Average age and ± SD	55 ± 11	59 ± 11
Cells analysed ( N)	3265	4365	4271	4369
Axial ratio average and ± SD	1.14 ± 0.15	1.25 ± 0.27	1.24 ± 0.26	1.27 ± 0.27
SIGNIFICANT DIFFERENCE BETWEEN GROUPS (p-values shown)
Healthy/Diab	Diab/DFX	Diab/DFO	DFX/DFO	Healthy/DFX	Healthy/DFO
1.1E-56	4.7E-02	2.6E-04	2.6E-04	2.9E-83	2.0E-02

Data provided for healthy individuals compared with untreated diabetes, diabetes treated with deferasirox (DFX) and deferoxamine (DFO). Untreated diabetes results were also compared (comparison done on a paired basis) with diabetes treated with DFX and DFO.