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Table 5 Average axial ratios of the groups and significant differences between the groups

From: Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics

 

Healthy individuals (no products added) (N = 25)

Untreated Diabetes (DIAB) (N = 69)

Diabetes with Deferasirox (DFX) (N = 69)

Diabetes with Deferoxamine (DFO) (N = 69)

Average age and ± SD

55 ± 11

59 ± 11

Cells analysed ( N)

3265

4365

4271

4369

Axial ratio average and ± SD

1.14 ± 0.15

1.25 ± 0.27

1.24 ± 0.26

1.27 ± 0.27

SIGNIFICANT DIFFERENCE BETWEEN GROUPS (p-values shown)

Healthy/Diab

Diab/DFX

Diab/DFO

DFX/DFO

Healthy/DFX

Healthy/DFO

1.1E-56

4.7E-02

2.6E-04

2.6E-04

2.9E-83

2.0E-02

  1. Data provided for healthy individuals compared with untreated diabetes, diabetes treated with deferasirox (DFX) and deferoxamine (DFO). Untreated diabetes results were also compared (comparison done on a paired basis) with diabetes treated with DFX and DFO.