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Table 2 Change in glucose and lipid metabolism after meal loading tests, preceded by placebo (baseline) or exenatide injection

From: Effects of exenatide on postprandial vascular endothelial dysfunction in type 2 diabetes mellitus

  Baseline Exenatide P value
Glucose metabolism variables    
 AUC of plasma glucose [(mg/dL) · hr] 855.4 ± 45.3 442.3 ± 26.4 0.001
 CV of plasma glucose 0.19 ± 0.02 0.20 ± 0.01 0.776
 AUC of IRI [(μIU/mL) · hr] 96.7 ± 18.5 84.6 ± 28.9 0.211
 CV of IRI 0.49 ± 0.04 0.53 ± 0.05 0.427
Lipid metabolism variables    
 AUC of TG [(mg/dL) · hr] 616.8 ± 68.7 475.5 ± 45.7 0.001
 CV of TG 0.14 ± 0.02 0.06 ± 0.02 0.001
 AUC of HDL-C [(mg/dL) · hr] 171.8 ± 12.2 177.2 ± 13.4 0.064
 CV of HDL-C 0.03 ± 0.003 0.03 ± 0.003 0.730
 AUC of LDL-C [(mg/dL) · hr] 419.0 ± 35.1 436.3 ± 32.8 0.221
 CV of LDL-C 0.03 ± 0.003 0.03 ± 0.003 0.875
  1. Data are mean ± SEM.
  2. Abbreviations: AUC area under the curve, CV coefficient of variation, IRI immunoreactive insulin, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol.