Median changes in A1C and FPG, by end-point body weight change quartiles. (A) A1C. (B) FPG. A1C, hemoglobin A1C; FPG, fasting plasma glucose. The central line represents the median (also labelled above the plot), the box encloses the 25th to 75th percentiles of the distribution, and the outer bars are drawn to the 10th and 90th percentiles.