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Table 3 Crude and adjusted odds ratios for the presence of any grade of diastolic dysfunction according to quartiles of insulin resistance and metabolic syndrome status

From: Diastolic dysfunction in the diabetic continuum: association with insulin resistance, metabolic syndrome and type 2 diabetes

 

Prevalence of LVDD n (%)

Crude OR (95% CI)

Adjusted OR* (95% CI)

Insulin resistance

   

(HOMA-IR score)

   

  Quartile 1

35 (14.9%)

Reference

Reference

  Quartile 2

42 (18.6%)

1.30 (0.80-2.13)

1.08 (0.63-1.86)

  Quartile 3

70 (29.3%)

2.37 (1.50-3.73)

1.88 (1.12-3.14)

  Quartile 4

89 (30.6%)

2.52 (1.63-3.90)

1.82 (1.09-3.03)

No Metabolic Syndrome (n = 571)

93 (16.3%)

Reference

Reference

Metabolic Syndrome without T2DM (n = 331)

108 (32.6%)

2.54 (1.85-3.50)

1.62 (1.12-2.36)

Metabolic Syndrome with T2DM (n = 123)

45 (36.6%)

3.04 (1.98-4.67)

1.78 (1.09-2.91)

  1. T2DM: type 2 diabetes mellitus; LVDD: left ventricular diastolic dysfunction; HOMA-IR - Homeostasis Model Assessment of Insulin Resistance;
  2. OR (95% CI) – odds ratio with 95% confidence interval.
  3. *Variables included in the model: age (continuous), sex, systolic blood pressure (continuous) and body mass index (continuous).
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Cardiovascular Diabetology

ISSN: 1475-2840