Figure 2
α-adrenoceptor agonist responses in Zucker Diabetic Fatty rats. Peak change in mean arterial pressure (top) and heart rate (bottom) in response to 1–100 μg.kg−1 phenylephrine under conscious conditions (a and c) and during isoflurane anaesthesia (b and d). *significantly different from non-diabetic littermate controls, †significantly different from conscious measure and # significant overall group difference, n = 8, p < 0.05, values are means ± SE.