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Table 1 Characterization of AGE-LDL

From: Immunization with advanced glycation end products modified low density lipoprotein inhibits atherosclerosis progression in diabetic apoE and LDLR null mice

 

nLDL

ox-LDL

AGE-LDL

TBA (nmoles HMF/mg protein)

1.92 ± 1.30

4.41 ± 1.22*

7.35 ± 0.83**#

TNBSA (AU)

0.45 ± 0.08

0.40 ± 0.07*

0.32 ± 0.04*

TBARS (nmoles MDA/mg protein)

0.30 ± 0.21

4.17 ± 0.06**

1.82 ± 0.31*#

Rf (cm)

0.51 ± 0.05

0.63 ± 0.08*

0.74 ± 0.05*

  1. *indicates p < 0.05 vs. nLDL, **indicates p < 0.01 vs. nLDL and #indicates p < 0.05 vs. ox-LDL; nLDL: native low density lipoprotein; TBA: thiobarbituric assay; HMF: 5-hydroxymethylfurfural; TNBSA: trinitrobenzene sulphonic acid assay; TBARS: thiobarbituric acid reactive substances; MDA: malondialdehyde; Rf: relative electrophoretic mobility by agarose gel electrophoresis.
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Cardiovascular Diabetology

ISSN: 1475-2840