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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Immunization with advanced glycation end products modified low density lipoprotein inhibits atherosclerosis progression in diabetic apoE and LDLR null mice

Figure 3

Serum titers of IgG, IgM, IgG1 and IgG2a antibodies. A. ELISA analysis of titers of IgG, IgM, and specific anti-AGE-LDL IgG and IgM antibodies in sera from diabetic apoE-/- and LDLR-/- mice (n = 10 per group) treated with Alum adjuvant (bar with stripes), AGE-LDL + Alum adjuvant (black bar) or PBS controls (white bar). B. ELISA analysis of specific IgG1 and IgG2a antibodies against AGE-LDL in sera from diabetic apoE-/- and LDLR-/- mice treated with Alum adjuvant, AGE-LDL + Alum adjuvant or PBS controls. C shows the ratio of serum IgG1/IgG2a antibodies among three groups. *indicates p < 0.05 vs. control, **indicates p < 0.01 vs. control, and #indicates p < 0.05 vs. Alum.

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Cardiovascular Diabetology

ISSN: 1475-2840