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Figure 3 | Cardiovascular Diabetology

Figure 3

From: PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors

Figure 3

Effect of PPARγ agonist rosiglitazone (ROSI, 10 μmol/L, 24 h) on expression of proangiogenic genes in PACs from wild type (WT) and diabetic (db/db) mice. PACs cultured without ROSI are used as a control. A: VEGF. B: KDR. C: Flt-1. D: SDF-1. E: CXCR4. F: CXCR7. G: KC. H: Angiotensinogen. I: PRG-4. Quantitative RT-PCR. EF2 serves as an internal control. Each bar represents mean + SEM. N = 8-10, *p < 0.05, **p < 0.01 versus WT, #p < 0.05, ##p < 0.01, ###p < 0.001 versus control.

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Cardiovascular Diabetology

ISSN: 1475-2840