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Table 1 GW3965 attenuated diabetes-induced metabolism abnormalities

From: Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice

Group

Body weight

Blood glucose

TC

TG

(g)

(mmol/L)

(mmol/L)

(mmol/L)

db/+

27.84 ± 0.52

7.00 ± 0.53

2.08 ± 0.04

0.89 ± 0.02

db/+ GW

27.76 ± 0.60

5.30 ± 0.56

2.13 ± 0.13

0.97 ± 0.02

db/db

54.85 ± 0.70*

19.93 ± 1.56*

4.31 ± 0.15*

1.56 ± 0.04*

db/db GW

45.28 ± 0.66*#

7.00 ± 0.97#

2.91 ± 0.13*#

1.71 ± 0.04*

  1. Fasting blood glucose, TC, TG levels and body weight were all measured on the day of animal sacrifice. Data are means ± SEM; *P < 0.05 vs db/+ group; #P < 0.05 vs db/db group; n =8-10. Abbreviations: GW GW3965, TC total cholesterol, TG triglycerides.
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Cardiovascular Diabetology

ISSN: 1475-2840