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Table 1 Baseline characteristics of study subjects

From: Effects of pitavastatin versus atorvastatin on the peripheral endothelial progenitor cells and vascular endothelial growth factor in high-risk patients: a pilot prospective, double-blind, randomized study

 

Pitavastatin

Atorvastatin

P value

(n = 13)

(n = 13)

Age (years)

60.1 ± 7.3

60.5 ± 10.3

0.90

Male, n (%)

6 (46.2%)

5 (38.5%)

0.69

Type 2 Diabetes Mellitus, n (%)

8 (61.5%)

11 (84.6%)

0.38

Hypertension, n (%)

10 (70.7%)

7 (53.8%)

0.67

Coronary artery disease, n (%)

2 (15.4%)

0 (0.0%)

0.14

Current smoker, n (%)

2 (15.4%)

1 (7.7%)

0.54

Waist Circumference (cm)

87.7 ± 6.3

91.7 ± 13.1

0.33

BMI (kg/m2)

25.2 ± 3.9

27.1 ± 3.8

0.22

SBP (mmHg)

118.2 ± 12.6

127.5 ± 19.6

0.17

DBP (mmHg)

76.2 ± 8.9

80.8 ± 11.1

0.26

HR (/min)

73.5 ± 11.7

75.7 ± 10.9

0.63

Creatinine (μmol/L)

76.9 ± 19.4

70.7 ± 17.7

0.25

ALT (U/L)

21.7 ± 13.5

33.6 ± 21.1

0.10

Glucose (mmo/L)

6.98 ± 1.39

6.28 ± 1.04

0.16

A1c (%)

6.8 ± 1.1

6.3 ± 0.5

0.18

Medication

   

Metformin, n (%)

8 (61.5%)

11 (84.6%)

0.14

DPP-4 inhibitors, n (%)

2 (15.4%)

1 (7.7%)

0.54

PPAR-γ agonists, n (%)

0 (0%)

1 (7.7%)

0.31

ARB, n (%)

3 (23.1%)

4 (30.8%)

0.66

ACEI, n (%)

3 (23.1%)

2 (15.4%)

0.62

CCB, n (%)

5 (38.5%)

3 (23.1%)

0.40

Beta-blockers, n (%)

2 (15.4%)

2 (15.4%)

1.00

Diuretics, n (%)

1 (7.7%)

4 (30.8%)

0.14

Aspirin, n (%)

3 (23.1%)

1 (7.7%)

0.28

  1. Values are mean ± standard deviation (SD) or number (%). ARB: angiotensin II receptor blockers; ACEI: angiotensin converting enzyme inhibitors; BMI: body mass index; CCB: calcium channel blockers; DBP: diastolic blood pressure; HR: heart beats ALT: analine amiontransferase; DPP-4 inhibitors: dipeptidyl peptidase-4 inhibitors; PPAR-γ agonists: peroxisome proliferator activator receptor-gamma agonists, SBP: systolic blood pressure.