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Table 2 Delay in Agonist-Induced Ca2+ Transient in SMC from Diabetic Animals

From: Intracellular Ca2+ regulating proteins in vascular smooth muscle cells are altered with type 1 diabetes due to the direct effects of hyperglycemia

 

Ca2+ Response (Time to Peak in seconds)

 

STZ-Induced Diabetic Rat Model

DR-BB Diabetic Rat Model

 

Control

Diabetic

Control

Diabetic

Vasopressin

17 ± 3

54 ± 14 *

22 ± 2

26 ± 3

Thapsigargin

35 ± 3

67 ± 9 *

41 ± 7

152 ± 23 *

  1. *Indicates a significantly different value when compared to respective controls (p < 0.05)
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Cardiovascular Diabetology

ISSN: 1475-2840