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Table 1 Clinical characteristics and biochemical assessments of study patients

From: Plasma concentrations of osteopontin, but not thrombin-cleaved osteopontin, are associated with the presence and severity of nephropathy and coronary artery disease in patients with type 2 diabetes mellitus

Variable

Control (n = 75)

Diabetes (n = 301)

Men/Female (n)

38/37

171/130

Age (years)

56.7 ± 10.5

65.5 ± 9.7*

Smokers (%)

14 (18.7)

88 (29.2)

Hypertension (%)

6 (8.0)

252 (83.7)*

   SBP (mmHg)

122 ± 15

136 ± 19*

   DBP (mmHg)

75 ± 8

79 ± 11†

Hyperlipidemia (%)

25 (33.3)

196 (65.1)*

   Triglyceride (mmol/L)

1.35 ± 0.65

2.08 ± 1.63*

   Total cholestrol(mmol/L)

4.30 ± 0.80

4.47 ± 1.00

   HDL-C (mmol/L)

1.33 ± 0.35

1.17 ± 0.31*

   LDL-C (mmol/L)

2.49 ± 0.55

2.55 ± 0.82

   Lipoprotein (a) (g/L)

0.23 ± 0.19

0.25 ± 0.20

Fast glucose (mmol/L)

4.85 ± 0.63

6.98 ± 2.56*

HbA1c (%)

-

7.57 ± 1.35

ACEI or ARB (%)

7 (9.3)

234 (77.7)*

Statins (%)

17 (22.7)

237 (78.7)*

  1. Data are given as either the number of patients (%), mean ± SD. *P < 0.001, †P < 0.01 compared with the control group.
  2. Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; HbA1c, glycated hemoglobin; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker