Early alterations in vascular contractility associated to changes in fatty acid composition and oxidative stress markers in perivascular adipose tissue

Table 2 Oxidative stress markers measured in PVAT of CD and FRD rats

	SOD (U/mg)	GSH-Px (U/mg)	GSH-Rd (U/mg)	TBARS (nmol/mg)	NO_x (pmol/mg)	GSH + GSSG (pmol/mg)
CD^a	7.96 ± 0.45	12.14 ± 0.94	19.60 ± 1.10	0.27 ± 0.01	110.18 ± 5.89	88.40 ± 4.42
FRD^b	4.98 ± 0.13	6.22 ± 0.27	26.85 ± 1.15	0.53 ± 0.03	215.38 ± 5.03	47.08 ± 1.98
a vs. b, P	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001

Values represent the means ± SEM. n = 7 animals for each group. CD: control; FRD: fructose-fed rats; SOD: superoxide dismutase; GSH-Px: glutathione peroxidase; GSH-Rd: glutathione reductase; TBARS: thiobarbituric acid reactive species; NOx: nitrates plus nitrites; GSH+GSSG: total content of glutathione in PVAT.

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