Therapies for type 2 diabetes: lowering HbA1c and associated cardiovascular risk factors

Table 2 Comparison of guidelines for the management of patients with type 2 diabetes mellitus [20, 22]

	HbA1c	Fasting Glucose	Postprandial Glucose	Blood Pressure	Lipids
AACE/ACE, 2007 [20]	≤ 6.5%	Fasting plasma glucose < 110 mg/dL	2-hr postprandial glucose < 140 mg/dL	< 130/80 mmHg	LDL-C < 100 mg/dL (< 70 mg/dL for patients with DM and coronary artery disease) HDL-C >40 mg/dL in men, > 50 mg/dL in women Triglycerides < 150 mg/dL
ADA, 2009 [22]	< 7.0%	Preprandial capillary plasma glucose, 70-130 mg/dL	Peak postprandial capillary plasma glucose < 180 mg/dL	< 130/80 mmHg	LDL-C < 100 mg/dL* HDL-C >40 mg/dL in men, > 50 mg/dL in women Triglycerides < 150 mg/dL

*In individuals with overt cardiovascular disease, a lower LDL-C goal of < 70 mg/dL (1.8 mmol/L), using high doses of a statin, is an option.
AACE, American Association of Clinical Endocrinologists; ACE, American College of Endocrinology; ADA, American Diabetes Association; DM, diabetes mellitus; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.

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