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Table 3 Concentrations of CRP according to the HNF1A G319S carrier status among participants without diabetes

From: Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

  Beta SE CRP [95% CI] (mg/L) * p
    G/G319 S/G + S/S319  
Model 1† -0.3525 0.1498 1.65 (1.23-2.22) 1.16 (0.93-1.46) 0.02
Model 2‡ -0.2803 0.1351 1.65 (1.26-2.15) 1.24 (0.95-1.62) 0.04
Model 3§ -0.3310 0.1215 1.66 (1.31-2.11) 1.19 (0.94-1.51) 0.007
Model 4 -0.2635 0.1008 1.64 (1.35-2.00) 1.26 (1.04-1.54) 0.009
  1. *Least square mean CRP values are back-transformed after using log-transformed CRP to calculate p-values. Group sample sizes of 477 (G/G319) and 104 (S/G + S/S319) have 90.8% power to detect a difference between mean CRP concentrations ± standard deviations of 1.65 (G/G319) ± 1.39 and 1.16 (S/G + S/S319) ± 1.36 at a significance level of 0.05. †Model 1: unadjusted ‡Model 2: adjusted for age, sex, log 2-h post-load glucose §Model 3: adjusted for model 2 variable and waist circumference Model 4: adjusted for model 3 variables and log serum amyloid A