| | Beta | SE | CRP [95% CI] (mg/L) * | p |
|---|
| | | | G/G319 | S/G + S/S319 | |
|---|
Model 1†| -0.3525 | 0.1498 | 1.65 (1.23-2.22) | 1.16 (0.93-1.46) | 0.02 |
Model 2‡ | -0.2803 | 0.1351 | 1.65 (1.26-2.15) | 1.24 (0.95-1.62) | 0.04 |
Model 3§ | -0.3310 | 0.1215 | 1.66 (1.31-2.11) | 1.19 (0.94-1.51) | 0.007 |
Model 4∥ | -0.2635 | 0.1008 | 1.64 (1.35-2.00) | 1.26 (1.04-1.54) | 0.009 |
- *Least square mean CRP values are back-transformed after using log-transformed CRP to calculate p-values. Group sample sizes of 477 (G/G319) and 104 (S/G + S/S319) have 90.8% power to detect a difference between mean CRP concentrations ± standard deviations of 1.65 (G/G319) ± 1.39 and 1.16 (S/G + S/S319) ± 1.36 at a significance level of 0.05. †Model 1: unadjusted ‡Model 2: adjusted for age, sex, log 2-h post-load glucose §Model 3: adjusted for model 2 variable and waist circumference ∥Model 4: adjusted for model 3 variables and log serum amyloid A
