Continuous glucose monitoring with Humalog Mix 25 versus Humalog Mix 50, twice daily: A comparative pilot study -Results from the Jikei-EValuation of insulin Lispro mixture on pharmacodynamics and glycemic VariancE (J-EVOLVE) study

Table 2 Indices (mean ± SD) for glycemic variation with twice-daily Mix 25 vs. Mix 50 regimens in 11 type 2 diabetic patients

	Mix 25 regimen	Mix 50 regimen	P value*
24-hour mean glucose concentration (mg/dL)	176 ± 54	187 ± 41	0.231
SD for 24-hour mean glucose concentration (mg/dL)	50 ± 16	49 ± 11	0.962
Mean glucose concentration 0-8 hrs (mg/dL)	127 ± 52	147 ± 42	0.024
Mean glucose concentration 8-24 hrs (mg/dL)	199 ± 59	206 ± 45	0.514
Lowest glucose concentration (mg/dL)	95 ± 49	105 ± 29	0.464
Peak glucose concentration (mg/dL)	276 ± 62	299 ± 43	0.061
Mean pre-meal glucose concentration (mg/dL)
Pre-breakfast	144 ± 54	172 ± 45	0.496
Pre-lunch	151 ± 72	153 ± 55	0.349
Pre-supper	161 ± 60	177 ± 60	0.997
Increase in postprandial peak glucose concentration (mg/dL)
Post-breakfast	93 ± 35	85 ± 28	0.366
Post-lunch	113 ± 43	138 ± 46	0.949
Post-supper	76 ± 28	59 ± 36	0.287
Time to postprandial peak glucose concentration (minutes)
Post-breakfast	98 ± 38	93 ± 37	0.667
Post-lunch	136 ± 34	131 ± 21	0.658
Post-supper	81 ± 23	71 ± 21	0.358

ISSN: 1475-2840