Genetic variation in the adiponectin receptor 2 (ADIPOR2) gene is associated with coronary artery disease and increased ADIPOR2 expression in peripheral monocytes

Table 1 Anthropometric and metabolic characteristics of the people studied

	NonCAD (n = 28)	CAD (n = 40)	p
*Anthropometric characteristics*
Age (years)	56.61 ± 1.47	59.80 ± 1.34	NS
Body weight (kg)	80.28 ± 2.09	83.69 ± 1.51	NS
BMI (Kg/m²)	28.12 ± 0.51	28.53 ± 0.49	NS
WHR	0.93 ± 0.01	0.99 ± 0.01	0.001
*Metabolic characteristics & Indices*
Fasting plasma glucose (mg/dl)	106.76 ± 6.19	113.29 ± 4.5	NS
Two-hour plasma glucose (mg/dl)	162.81 ± 15.30	199.35 ± 12.79	NS
Fasting plasma insulin (μU/ml)	14.39 ± 1.84	13.79 ± 1.15	NS
Two-hour plasma insulin (μU/ml)	100.09 ± 12.74	135.41 ± 22.53	NS
HOMA index	3.80 ± 0.58	4.68 ± 0.69	NS
Matsuda index	2.84 ± 0.24	2.68 ± 0.25	NS
Total cholesterol (mg/dl)	193.26 ± 8.55	183.32 ± 5.85	NS
LDL (mg/dl)	128.00 ± 8.68	122.71 ± 4.88	NS
HDL (mg/dl)	49.29 ± 2.62	45.97 ± 1.97	NS
Trigycerides (mg/dl)	114.46 ± 10.04	133.39 ± 10.95	NS
Systolic blood pressure (mm Hg)	122.32 ± 2.94	128.06 ± 2.57	NS
Diastolic blood pressure (mm Hg)	76.25 ± 1.76	78.89 ± 1.34	NS
IMT(mm)	0.83 ± 0.05	1.09 ± 0.05	0.001
IMT bulb (mm)	1.13 ± 0.15	1.45 ± 0.08	NS
FMD (%)	8.59 ± 1.28	7.01 ± 0.81	NS
Adiponectin (μg/ml)	13.01 ± 1.09	13.18 ± 1.30	NS
ADIPOR2 mRNA (AU)	0.81 ± 0.06	1.2 ± 0.16	0.035
ADIPOR2 protein (MFI)	82.97 ± 9.83	65.60 ± 4.68	NS

Data are given as means ± SEM. BMI: Body Mass Index, LDL: Low Density Lipoprotein, HDL: High Density Lipoprotein, IMT: Intima Media Thickness; FMD: Flow Mediated Dilatation

ISSN: 1475-2840