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Table 1 Characteristics of ZL (+/+) and ZDF (fa/fa) rats at 14 weeks of age

From: Altered myocardial substrate metabolism is associated with myocardial dysfunction in early diabetic cardiomyopathy in rats: studies using positron emission tomography

 

ZL (+/+)

ZDF (fa/fa)

Caloric intake [kcal/wk/100 grBW]

149 ± 5

229 ± 12*

Body weight at killing [g]

296 ± 5

349 ± 4*

Water intake [ml/wk/100 grBW]

65 ± 5

264 ± 17*

Non-fasting BG [mmol/L]

5.4 ± 0.2

20.1 ± 1.0*

Hematocrit [%]

49.7 ± 1.6

54.4 ± 1.7

Fasting insulin [pmol/L]

66.0 ± 5.8

387.8 ± 74.4*

Fasting TG [mmol/L]

0.58 ± 0.07

2.11 ± 0.54*

Fasting FA [mmol/L]

0.62 ± 0.05

0.58 ± 0.05

M-value [mg/kg/min]

21.2 ± 1.2

8.4 ± 0.7 *

  1. Data are presented as mean ± SEM, n = 8–10, * p < 0.05 vs. ZL rats.
  2. ZL, Zucker lean; ZDF, Zucker diabetic fatty; BG, blood glucose; TG, triglyceride; FA, fatty acid.