|
Variable
|
Type 1 (n = 304)
|
Type 2 (n = 397)
|
|---|
|
No.
|
Δ HbA
1c
(%)
|
p-value†
|
No.
|
Δ HbA
1c
(%)
|
p-value†
|
|---|
|
Overall
|
304
|
-0.38
|
<0.001
|
397
|
-0.31
|
<0.001
|
|
HbA1c by baseline level
| | | | | | |
|
≥ 7%
|
259
|
-0.42
|
<0.001
|
327
|
-0.36
|
<0.001
|
|
≥ 8%
|
186
|
-0.57
|
<0.001
|
271
|
-0.47
|
<0.001
|
|
≥ 9%
|
107
|
-0.96
|
<0.001
|
162
|
-0.69
|
<0.001
|
|
≥ 10%
|
53
|
-1.07
|
<0.001
|
71
|
-0.97
|
<0.001
|
- *Adjusted for significantly correlated demographic and clinical covariates including concomitant use of bolus, age, weight, hypoglycaemia, and baseline HbA1c (in the 3 months prior to insulin initiation).
- †p-values by the paired t-test for difference in mean HbA1c following switch from NPH to glargine.
