Comparison of the effects of miglitol and mitiglinide on postprandial glucose and insulin metabolism after meal tolerance testing in patients with mild diabetes mellitus. A pre-specified breakfast was prepared, containing 63.8 g of carbohydrate, 24.6 g of protein, 11.0 g of fat, 1.2 g of sodium and a total of 466 calories. Three months of administration of both agents caused similar improvements in postprandial hyperglycemia, although different patterns of insulin secretion were observed (A). Serum cystatin C levels did not change in the miglitol group, although the levels increased in the mitiglinide group. Miglitol caused a significant decrease in hsCRP levels whereas mitiglinide did not (B).