Table 5 Annual average drug costs per patient for different antihypertensives according to the pattern of persistence [23]
| Antihypertensive |
Continuers [95%CI] |
Switchers [95%CI] |
Discontinuers 95%CI] |
Total [95%CI] |
|---|---|---|---|---|
| Diuretics |
€ 65.09 [58.67–71.52] |
€ 153.10 [137.59–168.62] |
€ 8.17 [7.60–8.75] |
€ 33.45 [30.97–35.93] |
| Beta-blockers |
€ 109.29 [102.46–116.12] |
€ 158.73 [139.61–177.84] |
€ 22.52 [24.24-23.79] |
€ 63.40 [59.94–66.86] |
| Calcium-channel blockers |
€ 234.63 [224.78–244.47] |
€ 199.62 [183.45–215.78] |
€ 38.24 [36.78–39.70] |
€ 104.43 [100.07–108.79] |
| ACE inhibitors |
€ 196.28 [189.69–202.86] |
€ 237.53 [222.28–252.79] |
€ 34.76 [33.53–35.99] |
€ 108.25 [104.43–112.09] |
| Angiotensin II antagonists |
€ 326.16 [313.05–339.27] |
€ 268.07 [241.55–294.39] |
€ 67.10 [62.89–71.31] |
€ 201.53 [191.24–211.81] |
| Total |
€ 171.73
[167.43–176.04] |
€ 205.10
[196.85–213.34] |
€ 28.29
[27.62–28.97] |
€ 88.09
[86.10–90.08] |