Table 5 Annual average drug costs per patient for different antihypertensives according to the pattern of persistence [23]
Antihypertensive | Continuers [95%CI] | Switchers [95%CI] | Discontinuers 95%CI] | Total [95%CI] |
|---|---|---|---|---|
Diuretics | € 65.09 [58.67–71.52] | € 153.10 [137.59–168.62] | € 8.17 [7.60–8.75] | € 33.45 [30.97–35.93] |
Beta-blockers | € 109.29 [102.46–116.12] | € 158.73 [139.61–177.84] | € 22.52 [24.24-23.79] | € 63.40 [59.94–66.86] |
Calcium-channel blockers | € 234.63 [224.78–244.47] | € 199.62 [183.45–215.78] | € 38.24 [36.78–39.70] | € 104.43 [100.07–108.79] |
ACE inhibitors | € 196.28 [189.69–202.86] | € 237.53 [222.28–252.79] | € 34.76 [33.53–35.99] | € 108.25 [104.43–112.09] |
Angiotensin II antagonists | € 326.16 [313.05–339.27] | € 268.07 [241.55–294.39] | € 67.10 [62.89–71.31] | € 201.53 [191.24–211.81] |
Total | € 171.73 [167.43–176.04] | € 205.10 [196.85–213.34] | € 28.29 [27.62–28.97] | € 88.09 [86.10–90.08] |