Does the association of the triglyceride to high-density lipoprotein cholesterol ratio with fasting serum insulin differ by race/ethnicity?

Table 1 Geometric means of triglycerides, HDL-C, the TG/HDL-C ratio, and FSI by sex and race/ethnicity

	Non-Hispanic White (NHW)			Non-Hispanic Black (NHB)			Mexican American (MA)			P value†
	Mean*	95% CI		Mean	95% CI		Mean	95% CI		NHB vs. NHW	MA vs. NHW	MA vs. NHB
Men	N = 770			N = 243			N = 346
Triglycerides (mmol/L)‡	1.46	1.38	1.54	1.03	0.95	1.12	1.46	1.31	1.63	<0.001	0.975	<0.001
HDL-C (mmol/L)§	1.13	1.11	1.16	1.28	1.24	1.33	1.12	1.09	1.15	<0.001	0.588	<0.001
TG/HDL-C ratio	1.29	1.20	1.38	0.81	0.73	0.90	1.30	1.14	1.49	<0.001	0.863	<0.001
FSI (pmol/L)\|\|	58.0	55.3	60.9	56.4	52.4	60.7	69.4	65.1	73.8	0.494	<0.001	<0.001
Women	N = 737			N = 236			N = 320
Triglycerides (mmol/L)	1.27	1.23	1.32	0.94	0.88	1.00	1.30	1.21	1.40	<0.001	0.671	<0.001
HDL-C (mmol/L)	1.43	1.39	1.46	1.39	1.34	1.44	1.28	1.24	1.31	0.287	<0.001	<0.001
TG/HDL-C ratio	0.89	0.85	0.94	0.67	0.62	0.73	1.02	0.93	1.11	<0.001	0.030	<0.001
FSI (pmol/L)	51.1	48.9	53.4	67.8	62.7	73.3	67.9	61.6	74.9	<0.001	<0.001	0.966

HDL = high-density lipoprotein; FSI = fasting serum insulin; CI = confidence interval. * Weighted unadjusted geometric means.
† P-values indicate the significance of the differences in the means of triglycerides, HDL-C, the TG/HDL-C ratio, and FSI between two racial/ethnic groups. NHW = non-Hispanic white, NHB = non-Hispanic black, MA = Mexican American. Significance level with Bonferroni adjustment for multiple comparisons is 0.05/3 ≈ 0.017.
‡ To convert triglyceride concentration to mg/dl, divide concentration in mmol/L by 0.01129.
§To convert HDL-C concentration to mg/dl, divide concentration in mmol/L by 0.02586.
|| To convert FSI concentration to μU/mL, divide concentration in pmol/L by 6.

ISSN: 1475-2840