Table 2 Genetic association analysis of CAPN5 and PPARD gene variants with obesity.
Gene | Genotype | Controls | Cases | P value | OR [CI] |
|---|---|---|---|---|---|
CAPN5 (rs7102149) | GG | 498 | 299 | 0.899 | 1.01 [0.85–1.21] |
GA | 550 | 332 | 0.342 | 1.09 [0.91–1.30] | |
AA | 180 | 94 | 0.126 | 0.82 [0.63–1.06] | |
PPARG (rs2938392) | CC | 366 | 215 | 0.885 | 0.99 [0.81–1.20] |
CT | 597 | 333 | 0.346 | 0.92 [0.77–1.01] | |
TT | 265 | 177 | 0.199 | 1.15 [0.93–1.43] | |
PPARD (rs2076167) | AA | 639 | 348 | 0.295 | 0.91 [0.76–1.09] |
AG | 494 | 300 | 0.843 | 0.98 [0.81–1.18] | |
GG | 95 | 77 | 0.027 | 1.43 [1.04–1.97] |