First-line antihypertensive treatment in patients with pre-diabetes: Rationale, design and baseline results of the ADaPT investigation

Table 2 ADaPT study plan

Documentation/Investigation	Baseline	12 wk	6 mo	1 yr	2 yr	3 yr	4 yr
Clinical examination and medical history	x
Information on data protection	x
Blood pressure, heart rate	x	x	x	x	x	x	x
Physical examination: height, weight, waist and hip circumference	x			x	x	x	x
Laboratory screening (central laboratory): Blood glucose, HbA1c	x	x	x	x	x	x	x
Laboratory values: hsCRP, total cholesterol, LDL-C, HDL-C, TG, cystatin C, potassium, albumin, OGTT	x			x	x	x	x
ABPM (optional)	x			x	x	x	x
AE, SAE		x	x	x	x	x	x

Wk = weeks; mo = months; yr = years; hsCRP = high sensitive C-reactive protein; ABPM = ambulatory blood pressure monitoring; AE = Adverse Events; SAE = Serious Adverse Events

ISSN: 1475-2840