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Table 2 Previously identified variant (s) in IRS-1 gene in rats

From: Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats

Gene Strain Type Residue SNP Amino Acid
IRS-1 Sprague Dawley
Ref: Brown Norway
Non-synonymous 1160 ENSRNOSNP2552231 T/C
  1. Table showing previously reported IRS-1 variant in Sprague Dawley rats compared to Brown Norway rats. The IRS-1 non-synonymous variant caused an amino acid change from Cysteine to Tyrosine. Functional assessment of such variant is yet to be determined [133].