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Table 2 Previously identified variant (s) in IRS-1 gene in rats

From: Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats

Gene

Strain

Type

Residue

SNP

Amino Acid

IRS-1

Sprague Dawley

Ref: Brown Norway

Non-synonymous

1160

ENSRNOSNP2552231

T/C

  1. Table showing previously reported IRS-1 variant in Sprague Dawley rats compared to Brown Norway rats. The IRS-1 non-synonymous variant caused an amino acid change from Cysteine to Tyrosine. Functional assessment of such variant is yet to be determined [133].