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Table 4 Contrast between day- and night-time effects of rosiglitazone on ambulatory BP at 12 months

From: Effect of the addition of rosiglitazone to metformin or sulfonylureas versus metformin/sulfonylurea combination therapy on ambulatory blood pressure in people with type 2 diabetes: A randomized controlled trial (the RECORD study)

  Background metformin Background sulfonylurea
  rosiglitazone vs sulfonylurea (difference (95% CI), p-value) rosiglitazone vs metformin (difference (95% CI), p-value)
Systolic BP (mmHg)   
   24-hour -2.7 (-4.9, -0.5), 0.016 -2.5 (-4.8, -0.2), 0.031
   Day-time -3.3 (-5.6, -1.0), 0.004 -1.6 (-3.9, 0.9), NS
   Night-time -1.5 (-3.9, 1.0), NS -4.0 (-6.6, -1.3), 0.004
Diastolic BP (mmHg)   
   24-hour -2.1 (-3.4, -0.7), 0.003 -3.1 (-4.5, -1.8), < 0.001
   Day-time -2.5 (-3.9, -1.0), 0.001 -2.5 (-3.9, -1.0), 0.001
   Night-time -1.3 (-2.9, 0.3), NS -4.0 (-5.7, -2.4), < 0.001