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Table 2 Blood pressure lowering medication at baseline and end of follow-up

From: Effect of the addition of rosiglitazone to metformin or sulfonylureas versus metformin/sulfonylurea combination therapy on ambulatory blood pressure in people with type 2 diabetes: A randomized controlled trial (the RECORD study)

 

Background metformin

Background sulfonylurea

 

+ rosiglitazone

+ sulfonylurea

+ rosiglitazone

+ metformin

Modified ITT population (n)

176

165

160

167

Type of medication (n (%))

    

   Baseline

    

    Any BP medication

119 (68)

112 (68)

104 (65)

114 (68)

    ACEi/ARB

91 (52)

83 (50)

80 (50)

88 (53)

    β-blocker

44 (25)

42 (25)

34 (21)

43 (26)

    CCB

37 (21)

33 (20)

28 (17)

36 (22)

    Diuretics

28 (16)

34 (21)

26 (16)

38 (23)

   End of follow-up*

    

    Any BP medication

131 (74)

124 (75)

119 (74)

121 (72)

    ACEi/ARB

99 (56)

93 (56)

89 (56)

92 (55)

    β-blocker

51 (29)

53 (32)

40 (25)

46 (27)

    CCB

47 (27)

39 (24)

32 (20)

40 (24)

    Diuretics

48 (27)

39 (24)

34 (21)

41 (25)

Number of drug classes (n (%))

    

   Baseline

    

    0

57 (32)

53 (32)

56 (35)

53 (32)

    1

62 (35)

47 (28)

51 (32)

47 (28)

    2

34 (19)

45 (27)

37 (23)

43 (26)

    3

17 (10)

15 (9)

14 (9)

20 (12)

    > 3

6 (3)

5 (3)

2 (1)

4 (2)

   End of follow-up

    

    0

45 (25)

41 (25)

41 (26)

46 (27)

    1

57 (32)

47 (28)

58 (36)

45 (27)

    2

34 (19)

47 (28)

41 (26)

50 (30)

    3

27 (15)

22 (13)

15 (9)

19 (11)

    > 3

13 (7)

8 (5)

5 (3)

7 (4)

  1. Data are n or n (%).
  2. ACEi, ACE inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker.
  3. *End of follow-up refers to time of stopping dual combination therapy or 12 months, whichever is sooner