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Table 1 Patient characteristics and associations of sRAGE and esRAGE with different variables in 110 patients with type 2 diabetes

From: Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes

  

sRAGE#

esRAGE#

Characteristics

univariate (R)

multivariate (β)

univariate (R)

multivariate (β)

Age (years)

59 ± 7

0.22*

-

0.23*

0.24**

Gender (f/m)

24/86

-

0.21*

-

-

Diabetes duration (years)

13 ± 8

0.11

-

0.11

-

BMI (kg/m2)

33 ± 6

0.04

-

-0.04

-

HbA1c (%)

7.4 ± 1.2

-0.02

-

0.05

-

Fasting glucose (mmol/l)

8.2 ± 3.0

0.05

-

0.05

-

Glomerular filtration rate (ml/min)

128 ± 50

-0.15

-

-0.14

-

mean 24 h systolic BP (mmHg)

141 ± 16

0.02

-

-0.06

-

mean 24 h diastolic BP (mmHg)

80 ± 8

-0.14

-

-1.8

-

24 h Albumin excretion (mg)#

170 ± 406

0.18*

0.22*

0.10

-

Macrovascular Complications (%)

33

    

Retinopathy (%)

27

    

Polyneuropathy (%)

52

    

Insulin therapy (%)

64

    

ACE-Inhibitors/AT-R antagonists (%)

88

    
  1. Data is given as mean ± SD. R = Spearman correlation coefficient. β = standardized coefficient as given by stepwise multivariate regression analysis. # = variables were not normally distributed and log-transformed for multivariate analysis. * p ≤ 0.05, ** p ≤ 0.01
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Cardiovascular Diabetology

ISSN: 1475-2840