Table 2 Summary of metabolic markers at baseline and on the last day of combination therapy.
T/HCTZ | V/HCTZ | Difference* (T/HCTZ – V/HCTZ) | |||
|---|---|---|---|---|---|
Endpoint, mean ± SD | Baseline | Last day | Baseline | Last day | p value |
Serum triglyceride (mg/dL) | 201.7 ± 247 | 211.8 ± 172 | 196.3 ± 151 | 210.5 ± 177 | 0.91 |
LDL-C (mg/dL) | 165.6 ± 35.4 | 169.8 ± 38.1 | 162.8 ± 33.9 | 165.3 ± 36.0 | 0.17 |
HDL-C (mg/dL) | 37.1 ± 6.5 | 36.6 ± 6.3 | 37.6 ± 7.2 | 37.1 ± 7.0 | 0.64 |
Total cholesterol (mg/dL) | 195.7 ± 23.3 | 198.5 ± 21.7 | 194.5 ± 19.8 | 196.3 ± 20.9 | 0.20 |
Potassium (mEq/L) | 4.4 ± 0.4 | 4.5 ± 0.4 | 4.4 ± 0.4 | 4.4 ± 0.4 | 0.03 |
Glucose (mg/dL) | 128.8 ± 44.1 | 138.8 ± 53.1 | 134.1 ± 49.2 | 140.4 ± 55.2 | 0.58 |
HbA1c (%) | 6.5 ± 0.3 | 6.6 ± 0.3 | 6.6 ± 0.3 | 6.7 ± 0.4 | 0.93 |
Albumin:creatinine ratio | 97.6 ± 330 | 65.1 ± 266 | 66.7 ± 239 | 45.1 ± 177 | 0.97 |