Abdominal obesity exhibits distinct effect on inflammatory and anti-inflammatory proteins in apparently healthy Japanese men

Table 1 Characteristics of the study subjects

	All Subjects	Non-abdominal obesity group	Abdominal obesity group	P
n	326	163	163
Age, y	45.1 ± 8.1	45.3 ± 8.4	44.8 ± 7.7	n.s.
Waist, cm	84.8 ± 8.2	78.3 ± 4.7	91.2 ± 5.2	<0.0001
BMI, kg/m²	24.3 ± 3.3	22.1 ± 2.0	26.6 ± 2.8	<0.0001
SBP, mmHg	123 ± 16	120 ± 14	127 ± 17	<0.0001
DBP, mmHg	79 ± 12	76 ± 11	82 ± 13	<0.0001
TC, mg/dl	208 ± 35	203 ± 33	214 ± 37	0.003
TG, mg/dl	131 ± 128	100 ± 53	162 ± 168	<0.0001
HDL-C, mg/dl	58 ± 14	62 ± 15	53 ± 11	<0.0001
LDL-C, mg/dl	125 ± 34	120 ± 31	129 ± 37	0.03
FPG, mg/dl	91 ± 10	89 ± 9	93 ± 10	0.0009
HOMA-IR	1.35 ± 2.03	0.75 ± 0.29	1.87 ± 2.67	0.03
hs-CRP, mg/L	0.68 ± 0.77	0.58 ± 0.82	0.78 ± 0.71	0.018
IL-6, pg/ml	1.26 ± 0.75	1.18 ± 0.66	1.34 ± 0.83	0.045
Adiponectin, μg/ml	6.3 ± 2.9	7.1 ± 3.3	5.5 ± 2.1	< 0.0001

Data are mean ± SD. Abdominal obesity and non-abdominal obesity groups are the subjects who met or did not meet the waist criteria (≥ 85 cm). BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglycerides; HDL-C: HDL cholesterol; LDL-C: LDL cholesterol; FPG: fasting plasma glucose; HOMA-IR: homeostasis model assessment of insulin resistance; hs-CRP: high sensitive C reactive protein; IL-6: interleukin-6. Statistical significance was examined between non-abdominal obesity and abdominal obesity groups.

ISSN: 1475-2840