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Table 1 Clinical characteristics and metabolic parameters of male subjects with type-2 diabetes, pre-diabetes and no diabetes

From: Serum leptin and its relation to anthropometric measures of obesity in pre-diabetic Saudis

 

No Diabetes

Pre-diabetes

Type-2 Diabetes

N

45

49

97

Age (years)

45.7(12.6)

50.1(11.6)

54.5(10.7)f

Systolic blood pressure (mm Hg)

123.1(16.9)

132.8(25.1)a

130.7(17.5)

Diastolic blood pressure (mm Hg)

79.9(9.1)

85.1(11.4)

82.9(10.5)

BMI (Kg/m2)

29.2(7.3)

28.5(4.3)

27.3(4.1)

Waist (cm)

93.7(18.2)

98.6(10.1)

96.4(15.1)

Hips (cm)

95.9(15.7)

100.5(13.9)

99.8(14.4)

Fasting Glucose (mmol/L)

4.8(0.6)

6.1(0.4)f

13.7(5.0)f

Cholesterol (mmol/L)

5.2(1.6)

5.6(1.4)

6.5(1.9)f

HDL (mmol/L)

0.94(0.3)

1.2(0.4)

0.9(0.4)

Triglyceride (mmol/L)

1.8(0.6–6.7)

1.9(0.7–6.3)

2.5(1.6–15)

LDL (mmol/L)

3.3(1.1)

3.9(1.6)

4.2(1.8)b

Insulin μmol/L *

12.6(2–99)

12.3 (2–36)

16.2(2–70)

Leptin ng/mL *

3.9(0.8–20)

7.6(1.2–72)d

12.4(3.2–72)c

APO A1 mg/dL

0.9(0.3)

0.9(0.5)

0.9(0.3)

APO A2 mg/dL

0.4(0.1)

0.4(0.1)

0.3(0.1)

HOMA-IR *

3.3(0.3–23.8)

3.5(0.5–10.2)

9.6(1.1–49.7)e

  1. Data are presented as means (SD) or as medians (interquartile range) for insulin, leptin and HOMA-IR data. The P-values shown are comparisons of metabolic characteristics for case control versus either prediabetic patients or those with T2DM: a) 0.046; b) p = 0.03; c) p = 0.012; d) p = 0.004; e) p = 0.001; f) p < 0.0001.