Table 1 Characteristics of the LETO and OLETF rats in each groups
16-L | 16-O | 32-L | 32-O | 32-LT | 32-OT | |
|---|---|---|---|---|---|---|
(n = 8) | (n = 8) | (n = 8) | (n = 8) | (n = 7) | (n = 8) | |
Body Weight (g) | 383.8 ± 8.9 | 468.8 ± 10.6 ** | 460.8 ± 7.6 | 563.2 ± 15.2†† | 465.0 ± 14.9 | 521.4 ± 21.5 |
HbA1c (%) | 3.04 ± 0.07 | 3.18 ± 0.06 | 3.17 ± 0.07 | 4.45 ± 0.26†† | 3.09 ± 0.13 | 3.52 ± 0.07# |
Serum Insulin (ng/ml) | 1.5 ± 2.3 | 2.4 ± 0.8 | 1.7 ± 0.9 | 3.3 ± 1.1 | 1.6 ± 0.6 | 1.8 ± 0.2 |
Plasma glucose in OGTT (mg/dl) | ||||||
pre | 86.6 ± 2.2 | 100.9 ± 4.1* | 106.3 ± 3.7 | 122.3 ± 5.1† | 95.8 ± 2.0 | 98.8 ± 3.9# |
60 min | 131.1 ± 4.1 | 157.1 ± 14.4 | 142.5 ± 4.1 | 310.7 ± 5.0†† | 134.9 ± 1.7 | 225.6 ± 6.9## |
120 min | 102.6 ± 4.1 | 100.9 ± 1.9 | 101.9 ± 1.9 | 161.5 ± 4.8†† | 95.1 ± 3.1 | 98.9 ± 4.3## |