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Table 2 Plasma insulin and glucose levels as well as FMD during the oGTT (comparisons by paired Student's test, data represent mean ± standard deviation, #median)

From: Effect of repaglinide on endothelial dysfunction during a glucose tolerance test in subjects with impaired glucose tolerance

 

repaglinide

control

p

Fasting Insulin (mU/l)

7.16 ± 4.79

13.06 ± 20.97

n.s.

1 hour Insulin (mU/l)

72.40 ± 62.35

58.32 ± 48.39

n.s.*

2 hour Insulin (mU/l)

120.71 ± 86.78

49.83 ± 36.09

0.013*

Fasting glucose (mg/dl)

106.58 ± 12.38

109.1 ± 16.3

n.s.

1 hour glucose (mg/dl)

222.08 ± 30.05

213.7 ± 29.9

n.s.*

2 hour glucose (mg/dl)

138.33 ± 41.19

172.8 ± 48.4

<0.001***

Fasting FMD (%)

8.18 ± 2.93

7.98 ± 2.24

n.s.

1 hour FMD (%)

5.50 ± 3.11

5.58 ± 2.91

n.s.*

2 hour FMD (%)

7.24 ± 2.57

6.21 ± 2.69

n.s. (0.102)**

1 hour change FMD (%)#

-2.25

-1.95

n.s.*

2 hour change FMD (%)#

-1.05

-1.6

n.s.*

Fasting NMD (%)

15.09 ± 3.76

15.58 ± 3.74

n.s.

  1. *p < 0.001 vs. fasting for both groups
  2. **p = 0.028 vs. fasting for control, n.s. for repaglinide
  3. ***p < 0.001 vs. fasting for control, p = 0.005 for repaglinide