Skip to main content
Figure 1 | Cardiovascular Diabetology

Figure 1

From: Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products

Figure 1

a) One stage clotting assay: AGE stimulation of HUVEC resulted in enhanced tissue factor expression indicated by a reduction of clotting time. Activation of the tissue factor pathway was not observed with S100A8/S100A9 alone. * p < 0.05 as compared to control and S100A8/S100A9. b) Immunoblot showing upregulation of RAGE upon AGE stimulation in HUVEC. S100A8/S100A9 had no effect, while costimulation by AGE and S100A8/S100A9 exhibited no additional effect (not shown). The doubled bands are probably due to degradation of RAGE.

Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840