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Table 1 Baseline differences in subjects by CVD status

From: An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes

Trait

No CVD (n = 364)

CVD (n = 188)

P Value

Age (years)

65.5 (11.3)

69.6 (9.6)

<0.001

Duration (years)+

8 (4–15)

10 (5.5–17)

0.008

Systolic blood pressure (mmHg)*

141 (128–153)

139 (129–154)

0.340

Diastolic blood pressure (mmHg)*

81 (74–87)

76 (71–83)

0.004

Body mass index (kg/m2)*

29.17 (26.23–32.58)

29.08 (26.13–31.97)

0.262

HbA1c (%)*

7.6 (6.6–8.9)

7.4 (6.5–8.7)

0.336

Creatinine (mmol/l)*

88 (76–103)

99 (84–122)

<0.001

CRP (mg/l)*;

1.73 (1.06–3.18)

1.80 (0.99–3.34)

0.578

TAOS

42.50 (13.01)

41.83 (13.61)

0.578

Sex (F/M)

165/199 (45.3/54.7%)

57/131 (30.5/69.5%)

0.001

Normo/micro/proteinuria

201/128/35 (55.2/35.3/9.5%)

83/75/30 (44.1/39.9/16.0%)

0.019

Genotype distribution

155/165/44 (42.6/45.3/12.1%)

80/85/23 (42.6/45.2/12.2%)

0.999

ACEI (No/Yes)

197/167 (54.0/46.0%)

79/109 (42/58%)

0.008

Aspirin (No/Yes)

215/149 (59.2/40.8%)

50/138 (26.7/73.3%)

<0.001

Insulin (No/Yes)

280/84 (76.8/23.2%)

130/58 (69.1/30.9%)

0.052

Statin (No/Yes)

289/75 (79.3/20.7%)

85/103 (45.2/54.8%)

<0.001

  1. Mean (SD) or Median (Interquartile range) shown, *Log transformed, +Square root transformed. Analysis performed by two-sided T-tests after appropriate transformation. χ2 test were used to compare groups.