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Table 1 Baseline differences in subjects by CVD status

From: An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes

Trait No CVD (n = 364) CVD (n = 188) P Value
Age (years) 65.5 (11.3) 69.6 (9.6) <0.001
Duration (years)+ 8 (4–15) 10 (5.5–17) 0.008
Systolic blood pressure (mmHg)* 141 (128–153) 139 (129–154) 0.340
Diastolic blood pressure (mmHg)* 81 (74–87) 76 (71–83) 0.004
Body mass index (kg/m2)* 29.17 (26.23–32.58) 29.08 (26.13–31.97) 0.262
HbA1c (%)* 7.6 (6.6–8.9) 7.4 (6.5–8.7) 0.336
Creatinine (mmol/l)* 88 (76–103) 99 (84–122) <0.001
CRP (mg/l)*; 1.73 (1.06–3.18) 1.80 (0.99–3.34) 0.578
TAOS 42.50 (13.01) 41.83 (13.61) 0.578
Sex (F/M) 165/199 (45.3/54.7%) 57/131 (30.5/69.5%) 0.001
Normo/micro/proteinuria 201/128/35 (55.2/35.3/9.5%) 83/75/30 (44.1/39.9/16.0%) 0.019
Genotype distribution 155/165/44 (42.6/45.3/12.1%) 80/85/23 (42.6/45.2/12.2%) 0.999
ACEI (No/Yes) 197/167 (54.0/46.0%) 79/109 (42/58%) 0.008
Aspirin (No/Yes) 215/149 (59.2/40.8%) 50/138 (26.7/73.3%) <0.001
Insulin (No/Yes) 280/84 (76.8/23.2%) 130/58 (69.1/30.9%) 0.052
Statin (No/Yes) 289/75 (79.3/20.7%) 85/103 (45.2/54.8%) <0.001
  1. Mean (SD) or Median (Interquartile range) shown, *Log transformed, +Square root transformed. Analysis performed by two-sided T-tests after appropriate transformation. χ2 test were used to compare groups.