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Table 1 Baseline characteristics of subjects with normal glucose tolerance according to diabetes or not during 9 years of follow-up

From: High levels of tissue plasminogen activator (tPA) antigen precede the development of type 2 diabetes in a longitudinal population study. The Northern Sweden MONICA Study

  Non-DM DM p-value
n 536 15  
Age (years) 44.9 (10.9) 51.9 (8.7) 0.015
Sex (% men) 60 46 0.3
BMI (kg/m2) 25.0 (3.5) 28.4 (3.3) <0.001
Waist circumference (cm) 84.2 (11.0) 95.3 (9.8) <0.001
Diastolic blood pressure (mm Hg) 79.8 (10.7) 81.3 (10.8) 0.6
Triglycerides (mmol/l) 1.2 (0.9–1.7) [1.25] 2.1 (1.3–2.8) [1.95] < 0.001
Fasting plasma glucose (mmol/l) 5.16 (0.50) 5.89 (0.59) <0.001
Post load plasma glucose (mmol/l) 5.13 (1.12) 5.77 (1.04) 0.028
Fasting insulin (mU/ml) 5.0 (4.0–7.0) [5.7] 7.0 (8.0–10.0) [8.5] 0.002
tPA activity (IU/ml) 0.79 (0.56–1.0) [0.74] 0.59 (0.33–0.85) [0.54] 0.020
tPA antigen (μg/l) 5.7 (4.0 – 8.4) [5.7] 10.4 (9.0 – 13.7) [10.7] <0.001
PAI-1 activity (IU/ml) 6.1 (2.9 – 11.2) [6.2] 16.3 (7.1 – 18.8) [11.5] 0.003
  1. Data are means (SD), median (interquartile range) and [geometric means]. P values are for t test, or X2 test as appropriate.