Skip to main content

Table 1 Baseline characteristics of subjects with normal glucose tolerance according to diabetes or not during 9 years of follow-up

From: High levels of tissue plasminogen activator (tPA) antigen precede the development of type 2 diabetes in a longitudinal population study. The Northern Sweden MONICA Study

 

Non-DM

DM

p-value

n

536

15

 

Age (years)

44.9 (10.9)

51.9 (8.7)

0.015

Sex (% men)

60

46

0.3

BMI (kg/m2)

25.0 (3.5)

28.4 (3.3)

<0.001

Waist circumference (cm)

84.2 (11.0)

95.3 (9.8)

<0.001

Diastolic blood pressure (mm Hg)

79.8 (10.7)

81.3 (10.8)

0.6

Triglycerides (mmol/l)

1.2 (0.9–1.7) [1.25]

2.1 (1.3–2.8) [1.95]

< 0.001

Fasting plasma glucose (mmol/l)

5.16 (0.50)

5.89 (0.59)

<0.001

Post load plasma glucose (mmol/l)

5.13 (1.12)

5.77 (1.04)

0.028

Fasting insulin (mU/ml)

5.0 (4.0–7.0) [5.7]

7.0 (8.0–10.0) [8.5]

0.002

tPA activity (IU/ml)

0.79 (0.56–1.0) [0.74]

0.59 (0.33–0.85) [0.54]

0.020

tPA antigen (μg/l)

5.7 (4.0 – 8.4) [5.7]

10.4 (9.0 – 13.7) [10.7]

<0.001

PAI-1 activity (IU/ml)

6.1 (2.9 – 11.2) [6.2]

16.3 (7.1 – 18.8) [11.5]

0.003

  1. Data are means (SD), median (interquartile range) and [geometric means]. P values are for t test, or X2 test as appropriate.