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Table 3 Changes in cardiovascular medication

From: Multiple risk factor intervention reduces carotid atherosclerosis in patients with type 2 diabetes

 

Baseline (n = 97)

3 months (n = 94)

2 years (n = 77)

p-value (baseline - 3 months)

p-value (baseline - 2 years)

Glucose lowering treatment (%)

     

Metformin

62.9

75.5

67.1

0.001

0.655

Acarbose

3.1

2.1

1.2

0.320

0.317

Sulfonylureas

24.7

29.8

19.5

0.158

0.285

Glitazones

11.3

25.5

19.5

<0.001

0.058

DPP-IV Inhibitors

9.3

19.1

26.8

0.002

0.001

Insulin

26.8

32.3

29.3

0.027

0.105

Other OADs

3.1

3.3

2.4

1.000

0.564

Lipid lowering treatment (%)

     

Statins

35.1

73.4

68.3

<0.001

<0.001

Ezetimibe

4.1

4.3

1.2

1.000

0.157

Fibrates

6.2

7.5

4.8

0.564

1.000

Antihypertensive treatment (%)

     

ACE-Inhibitors

46.4

61.7

46.3

<0.001

1.000

Ca-channel blockers

21.6

47.9

46.3

<0.001

<0.001

Beta-blockers

35.1

40.4

42.7

0.102

0.109

AT2-blockers

21.6

28.7

30.0

0.033

0.132

Other Antihypertensives

37.1

46.8

42.5

0.020

0.516

  1. OAD = oral antidiabetic drugs; DPP-IV = Dipeptidylpeptidase IV; ACE = angiotensin converting enzyme; AT2 = angiontensin-2-receptor antagonist; ca-channel = calcium-channel.