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Figure 6 | Cardiovascular Diabetology

Figure 6

From: High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

Figure 6

Haematoxylin and eosin staining of the subendocardial zone to demonstrate cellular hypertrophy. Diabetic Ren-2 rats (b) demonstrated increased cardiomyocyte diameter when compared to control Ren-2 animals (a). Treatment with curcumin reduced pathological hypertrophy (c). Quantitative data presented in bottom right. (*p < 0.01 c/w control, †p < 0.05 c/w vehicle treated diabetic Ren-2 rats).

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Cardiovascular Diabetology

ISSN: 1475-2840