Figure 5
From: Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes
Effect of calpain inhibition on the ROS production and peroxynitrite formation in the aortas of diabetic mice. (A, B) ROS formation in the vessels assessed by DHE and DCF-DA staining, respectively. (C) Representative images for peroxynitrite formation in aortas from 4 mice in each group. a, WT mice; b, Tg-CAST mice; c, OVE26 mice; d, OVE26/Tg-CAST mice; e, STZ-injected wild-type (WT) mice; f, STZ-injected Tg-CAST mice; Data are given as mean ± SD, n = 6. *P < 0.05 vs. WT mice. #P < 0.05 vs. OVE26 mice.