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Table 2 Echocardiographic and CT parameters

From: Insulin resistance and subclinical abnormalities of global and regional left ventricular function in patients with aortic valve sclerosis

Variable

AVS+IR group

AVS-IR group

Control group

P Value§

(n = 28)

(n = 29)

(n = 28)

Peak transaortic velocity, m/s

1.6 ± 0.4*

1.6 ± 0.3*

1.2 ± 0.2

< 0.001

Mean transaortic pressure gradient, mm Hg

6 ± 2*

5 ± 2*

3 ± 1

< 0.001

LV mass index, g/m2.7

39 ± 6

36 ± 9

37 ± 5

0.20

LV hypertrophy, n (%)

3 (11)

3 (10)

0 (0)

0.19

LV end-diastolic volume, mL

85 ± 27

81 ± 20

83 ± 12

0.79

LV end-systolic volume, mL

27 ± 14

26 ± 13

26 ± 6

0.94

LV ejection fraction,%

70 ± 11

69 ± 8

68 ± 5

0.84

LV sphericity index

0.46 ± 0.04*†

0.43 ± 0.05*

0.40 ± 0.03

< 0.001

Left atrial volume index, mL/m2

29 ± 7*

29 ± 9*

25 ± 3

0.011

Transmitral E/A ratio

0.8 ± 0.4

0.8 ± 0.2

0.8 ± 0.1

0.59

Transmitral deceleration time, ms

233 ± 55

244 ± 50

224 ± 32

0.27

Pulmonary S/D ratio

1.6 ± 0.5

1.5 ± 0.3

1.5 ± 0.2

0.25

E/e’ ratio

12.5 ± 3.5*

11.1 ± 3.4*

8.5 ± 1.3

< 0.001

Longitudinal strain,%

-16.2 ± 1.6*†

-17.2 ± 1.2*

-18.9 ± 0.8

< 0.001

Longitudinal SR, s-1

-1.18 ± 0.26*†

-1.32 ± 0.21*

-1.52 ± 0.08

< 0.001

Longitudinal diastolic SR, s-1

1.09 ± 0.23*†

1.23 ± 0.18*

1.35 ± 0.12

< 0.001

Circumferential strain,%

-22.9 ± 0.8

-23.2 ± 0.6

-23.1 ± 0.7

0.31

Circumferential SR, s-1

-1.39 ± 0.04

-1.39 ± 0.04

-1.40 ± 0.05

0.91

Circumferential diastolic SR, s-1

1.90 ± 0.11

1.89 ± 0.08

1.88 ± 0.09

0.68

VAT area, cm2

113 ± 42

77 ± 38

…

0.001‡

SAT area, cm2

163 ± 74

127 ± 47

…

0.037‡

VAT/total fat ratio,%

42 ± 15

37 ± 13

…

0.18‡

Aortic valve calcium score

94 (11–197)

21 (6–54)

…

0.022‡

  1. Notes: Values are mean ± SD, number (percentage), or median (interquartile range). *P (with post hoc analysis) <0.05 versus control group. †P (with post hoc analysis) <0.05 versus the AVS-IR group. ‡P values are for χ2 test, Student t test, or Mann–Whitney U test for the AVS+IR versus the AVS-IR group. §P values are for 1-way ANOVA for all groups unless specified.
  2. Abbreviations: A late filling velocity; CT computed tomography; E early filling velocity; e’: early diastolic mitral annular velocity; HOMA homeostatic model assessment; LV left ventricular; SAT subcutaneous adipose tissue; S/D systolic/diastolic; SR strain rate; VAT visceral adipose tissue.