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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production

Figure 4

Effect of free radicals on the vasodilation due to exenatide. Concentration-relaxation curve of exenatide with/without the addition of 200 U/ml of the free radical scavanger superoxide dismutase (SOD) (A). Concentration-relaxation curve analyzing the possible role of hydrogen peroxide by blocking its formation with 1000 U/ml catalase (B). 23.9, 71.7, 310, 788, 1980, 3170 nanomoles of exenatide were used to relax the vessels (n = 5 of each experiment), *P < 0.01 compared to the relaxation caused by exenatide only (at respective concentration of exenatide).

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Cardiovascular Diabetology

ISSN: 1475-2840