| C | HF- | HF+ |
---|
HR | 347 ± 20 | 397 ± 9 | 370 ± 24 |
SP | 128 ± 4a | 164 ± 14b | 150 ± 14a,b |
DP | 21 ± 1 | 20 ± 1 | 21 ± 1 |
LVDP | 108 ± 4a | 144 ± 14b | 129 ± 14a,b |
dP/dt max | 3350 ± 206a | 4608 ± 530b | 4163 ± 531a,b |
dP/dt min | −3275 ± 180a | −4467 ± 457b | −3981 ± 513a,b |
- The number of experiments was 8, 4 and 4 for the C, HF- and HF + groups. The heart rate, pressures (systolic, diastolic and left ventricular developed pressures), dP/dt max and dP/dt min were expressed in beats/min, mmHg and mmHg/s. C: control; HF-: high fat-fed rats without weight gain; HF+: high fat-fed rats with weight gain; HR: heart rate; SP: systolic pressure; DP: diastolic pressure; LVDP: left ventricular developed pressure; dP/dt max: maximum rate of pressure change; dP/dt min: maximum rate of pressure change; a, b: two means located on a same line without a common letter are significantly different.